This study investigates how the evolution of the planetary boundary layer (PBL) influences new particle formation (NPF) events over Cyprus, a region impacted by both local and transported atmospheric conditions. Utilizing a combination of long-term ground-based observations and meteorological data, the research study emphasizes the presence of distinct patterns in PBL dynamics that correspond to the timing, intensity, and frequency of NPF events during the year 2022. The study’s key findings indicate that rapid morning PBL growth and vertical mixing processes play a critical role in transporting precursor gases and freshly formed particles, thereby modulating the onset and development of NPF.